Human trophoblast stem cells: Real or not real?
نویسندگان
چکیده
منابع مشابه
Human Adipose-Derived Stem/Stromal Cells from Children or Adults?
Discovering a cell type with the highest efficiency and the least side-effects is one of the priorities of scientists active in this field. Of all the cells, mesenchymal stem cells have been and still are of interest to the researchers for use in pre-clinical and clinical studies due to being easily accessible, pluripotency, secretion of numerous growth factors, low risk of immunological reject...
متن کاملHuman Trophoblast Progenitor Cells Express and Release Angiogenic Factors
Trophoblast stem cells develop from polar trophoectoderm and give rise to the cells that generate the placenta. Trophoblast cells are responsible for the uterinal invasion and vascular remodeling during the implantation of the embryo. However this knowledge is not yet to be confirmed for trophoblast progenitor cells (TPCs). In this study, we aimed to demonstrate that human TPCs (hTPCs) express ...
متن کاملHuman stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification.
Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four 8-cell embryos and one 12-cell embryo from a single couple. Compared with numerous conventional lines from blastocysts, they had unique gene expression and DNA methylation pattern...
متن کاملEvidence for bystander signalling between human trophoblast cells and human embryonic stem cells
Maternal exposure during pregnancy to toxins can occasionally lead to miscarriage and malformation. It is currently thought that toxins pass through the placental barrier, albeit bi-layered in the first trimester, and damage the fetus directly, albeit at low concentration. Here we examined the responses of human embryonic stem (hES) cells in tissue culture to two metals at low concentration. We...
متن کاملSynesthesia - A Real Phenomenon? Or Real Phenomena?
This text comments on Cytowic's recent review on the current knowledge on synesthesia. Recent neurophysiological findings are discussed that suggest crossmodal interference in the mammalian brain. Based on these results, it is proposed that synesthesia may not be restricted to the phenomenologically characterized abnormality described in Cytowic's review, but rather that it may encompass a seri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Placenta
سال: 2017
ISSN: 0143-4004
DOI: 10.1016/j.placenta.2017.01.003